Biological Activity for Cyclosporin H

Cyclosporin H is a viral transduction enhancer. Increases lentiviral transduction up to 10-fold in human cord blood-derived hematopoietic stem & progenitor cells (HSPCs). Displays an additive effect when combined with rapamycin (Cat. No. 1292) or prostaglandin E2 (Cat. No. 2296). Lacks immunosuppressant activity of cyclosporin A (Cat. No. 1101).

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Technical Data for Cyclosporin H

M. Wt 1202.64
Formula C62H111N11O12
Storage Store at -20°C
Purity ≥97% (HPLC)
CAS Number 83602-39-5
PubChem ID 6476564
InChI Key PMATZTZNYRCHOR-JLPRAAIDSA-N
Smiles H>(CC(C)C)N(C)C1=O)C(C)C

The technical data provided above is for guidance only. For batch specific data refer to lớn the Certificate of Analysis.

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Solubility Data for Cyclosporin H

Solvent Max Conc. Mg/mL Max Conc. Mm Solubility
DMSO 120.26 100
ethanol 60.13 50

Preparing Stock Solutions for Cyclosporin H

The following data is based on the product molecular weight 1202.64. Batch specific molecular weights may vary from batch khổng lồ batch due to the degree of hydration, which will affect the solvent volumes required to lớn prepare stock solutions.


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